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WHO 2016 systemic mastocytosis (Valent 2016 Table 1). Met when major…

WHO 2016 systemic mastocytosis (Valent 2016 Table 1). Met when major infiltrates (≥15 mast cells in aggregates in BM or extracutaneous organ) plus ≥1 minor, or ≥3 minors. Minors: >25% atypical/spindle mast cells, KIT codon 816, CD2 and/or CD25, tryptase >20 ng/mL (not valid with an unrelated myeloid neoplasm). Not a diagnosis. Not cutaneous mastocytosis only. Not ICC 2022. magent does not read a biopsy or assay tryptase.

Unavailable6 calls · 3 buyers in 30 days

Sample input

input3 keys
method"GET"
queryParams6 keys
associated_myeloid_neoplasmfalse
atypical_or_spindlefalse
cd2_or_cd25false
kit_codon_816true
major_infiltratestrue
tryptase_gt_20false
type"http"
inputobject, 3 keys

Sample response

response15 keys
associated_myeloid_neoplasmfalse
atypical_or_spindlefalse
cd2_or_cd25false
citation6 keys
authors"Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Horny HP, Galli SJ, Arock M, Metcalfe DD"
doi"10.1182/blood-2016-09-731893"
id"valent-2016"
pmid"28031180"
source"Blood. 2017;129(11):1420-1427 (Epub 2016 Dec 28)"
title"Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts"
criteria8 items
diagnosedtrue
disclaimer"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions."
formula"who_sm"
formula_expression"diagnosed iff (major_infiltrates and minor_count ≥ 1) or minor_count ≥ 3; minor_count counts atypical_or_spindle, kit_codon_816, cd2_or_cd25, and tryptase_gt_20 only when associated_myeloid_neoplasm is false (Valent 2016 Table 1 WHO SM). Not a diagnosis. Not cutaneous mastocytosis only. Not ICC 2022"
kit_codon_816true
majortrue
major_infiltratestrue
minor_count1
tryptase_countsfalse
tryptase_gt_20false
responseobject, 15 keys

Track record

Paid calls, last 30 days
6
Buyers, last 30 days
3
Last paid call

Reported by the x402 directory.

A$0.0072 per call

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